Human G6PC ELISA Kit
Supplier: CLOUD-CLONE CORP MS
This assay has high sensitivity and excellent specificity for detecting Human G6PC (Glucose to 6-Phosphatase, Catalytic). The assay range is from 0.156 to 10 ng/ml (Sandwich kit) with a sensitivity of 0.055 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
- High sensitivity and specificity
- Perfect reproducibility and consistency across batches
- Quality control with three-level inspections
- Wide range of targets/species available
- Intra-assay: CV<10%; Inter-assay: CV<12%
The basic defect resides in glucose-6-phosphatase. The liver and kidney are involved, and hypoglycemia is a major problem. Lipidemia also occurs and may lead to xanthoma formation. Survival to adulthood, previously rare, is now the usual situation. Hyperuricemia has been observed in a considerable number of patients and in some clinical gout has occurred. Inhibited tubular secretion of uric acid due to hyperlactic acidemia and ketonemia, and overproduction of uric acid have been postulated. The effects of glycerol administered by mouth on levels of glucose and of lactate, together with the response to epinephrine or glucagon, permitted differentiation of the several types of hepatic glycogenosis (I, II, III and IV). The glycogen storage diseases are notable examples of genetic heterogeneity.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
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