Human CRBN ELISA Kit

Supplier: CLOUD-CLONE CORP MS

SEG676HU
MSPP-SEG676HUEA 700 USD
MSPP-SEG676HU
Human CRBN ELISA Kit
Assays ELISAs

This assay has high sensitivity and excellent specificity for detecting Human CRBN (Cereblon). The assay range is from 0.156 to 10 ng/ml (Sandwich kit) with a sensitivity of 0.054 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.


  • High sensitivity and specificity
  • Perfect reproducibility and consistency across batches
  • Quality control with three-level inspections
  • Wide range of targets/species available
  • Intra-assay: CV<10%; Inter-assay: CV<12%


Cereblon is found on the human chromosome 3, on the short arm at position p26.3 from base pair 3,190,676 to base pair 3,221,394. CRBN orthologs are highly conserved from plants to humans. Cereblon forms an E3 ubiquitin ligase complex with damaged DNA binding protein 1 (DDB1), Cullin-4A (CUL4A), and regulator of cullins 1 (ROC1). This complex ubiquitinates a number of other proteins. Through a mechanism which has not been completely elucidated, this ubiquitination results in increased levels of fibroblast growth factor 8 (FGF8). FGF8 in turn regulates a number of developmental processes, such as limb and auditory vesicle formation. The net result is that this ubiquitin ligase complex is important for limb outgrowth in embryos.


Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Order Now


Learn more

About VWR

Avantor is a vertically integrated, global supplier of discovery-to-delivery solutions for...

Learn more About VWR