Human LAMP2 ELISA Kit
Supplier: CLOUD-CLONE CORP MS
This assay has high sensitivity and excellent specificity for detecting Human LAMP2 (Lysosomal Associated Membrane Protein 2). The assay range is from 62.5 to 4000 pg/ml (Sandwich kit) with a sensitivity of 24.9 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
- High sensitivity and specificity
- Perfect reproducibility and consistency across batches
- Quality control with three-level inspections
- Wide range of targets/species available
- Intra-assay: CV<10%; Inter-assay: CV<12%
Lysosomal Associated Membrane Protein 2 (LAMP2), also known as CD107b and Mac-3, is a glycoprotein found in the lysosomal membrane that plays a crucial role in cellular processes such as chaperone-mediated autophagy. LAMP2 is encoded by the LAMP2 gene, which can produce three isoforms: LAMP-2A, LAMP-2B, and LAMP-2C, each with distinct functions. LAMP-2A is involved in transporting proteins into lysosomes for degradation, LAMP-2B is essential for the fusion of autophagic vacuoles with lysosomes, and LAMP-2C is linked to the breakdown of nucleotides. Mutations in LAMP2 can lead to Danon disease, characterized by cardiomyopathy, myopathy, and intellectual disability, and have been associated with increased susceptibility to oxidative stress and ferroptosis. LAMP2 is also implicated in cancer metastasis, where it mediates tumor cell adhesion and invasion.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
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