Human PKM2 ELISA Kit
Supplier: CLOUD-CLONE CORP MS
This assay has high sensitivity and excellent specificity for detecting Human PKM2 (Pyruvate kinase isozymes M2). The assay range is from 78 to 5000 pg/ml (Sandwich kit) with a sensitivity of 29 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
- High sensitivity and specificity
- Perfect reproducibility and consistency across batches
- Quality control with three-level inspections
- Wide range of targets/species available
- Intra-assay: CV<10%; Inter-assay: CV<12%
Pyruvate Kinase M2 (M2-PK) is strongly overexpressed in a metabolic state specific for a variety of tumor cells. Recent reports indicate that Tumor M2-PK is a marker for renal cell carcinoma and. lung cancer. It has also been investigated in. pancreatic cancer and gastric cancer with promising results. M2-PK is encoded by the gene PKM2 which does also encode for the pyruvate kinase isoenzyme type M1 (PKM1 or M1-PK). The M-gene consists of 12 exons and 11 introns. PKM1 and PKM2 are different splicing products of the M-gene (exon 9 for PKM1 and exon 10 for PKM2) and solely differ in 23 amino acids within a 56 amino acid stretch (aa 378 to 434) at their carboxy terminus.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
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