Human PIIINP ELISA Kit
Supplier: CLOUD-CLONE CORP MS
This assay has high sensitivity and excellent specificity for detecting Human PIIINP (Procollagen III N to Terminal Propeptide). The assay range is from 0.625 to 40 ng/ml (Sandwich kit) with a sensitivity of 0.241 ng/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
- High sensitivity and specificity
- Perfect reproducibility and consistency across batches
- Quality control with three-level inspections
- Wide range of targets/species available
- Intra-Assay: CV <10%, Inter-Assay: CV <12%
Plasma levels of PIIINP a marker of extracellular matrix metabolism activity have been linked to abdominal aortic aneurysm growth rate, but its relationship with thoracic aortic aneurysm (TAA) growth has never previously been studied. The PIIINP molecule is an indicator of both the synthesis and the degradation of type III collagen. Occasionally, the removal of PIIINP from the newly-synthesized type III collagen is not complete and the propeptide may remain attached to some of the molecules, known as type IIIpN-collagen. PIIINP is a degradation product of type IIIpN collagen. PIIINP has a molecular weight of 42000 and contains three distinct domains: a triple-helical domain (Col 3) in the middle of the molecule, the Col 1-domain at the aminoterminal and Col 2-domain at the carboxyterminal end of the propeptide. PIIINP is cleared from the circulation by scavenger receptors in liver endothelial cells.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
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