Mouse GSN ELISA Kit
Supplier: CLOUD-CLONE CORP MS
This assay has high sensitivity and excellent specificity for detecting Mouse GSN (Gelsolin). The assay range is from 78 to 5000 pg/ml (Sandwich kit) with a sensitivity of 37 pg/ml. There is no detectable cross-reactivity with other relevant proteins. Activity loss rate and accelerated stability test ect have been conducted to guarantee the best performance of the products after long storage and delivery.
- High sensitivity and specificity
- Perfect reproducibility and consistency across batches
- Quality control with three-level inspections
- Wide range of targets/species available
- Intra-assay: CV<10%; Inter-assay: CV<12%
Gelsolin is an actin-regulatory protein that modulates actin assembly and disassembly, and is believed to regulate cell motility in vivo through modulation of the actin network. In addition to its actin-regulatory function, gelsolin has also been proposed to affect cell growth.It is first isolated from rabbit lung macrophages as a modulator of the cytoplasmic actin gel−sol transformation. Gelsolin can sever actin filaments and cap the fast-growing ends of the filaments in vitro; this promotes actin disassembly. Gelsolin also has the ability to nucleate actin polymerization. These functions are activated by Ca₂ and inhibited by polyphosphoinositides (PPIs). Such observations have led to the view that gelsolin regulates actin reorganization in response to changes in the concentrations of Ca₂ and PPIs in living cells.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
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