Polyclonal Antibody to Pregnancy Zone Protein (PZP), derived from recombinant PZP (Val1212~Met1391), is reactive with Human.
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Pregnancy zone protein (PZP), one of the major pregnancy-associated plasma proteins, was described by Smithies (1959) who used zone-electrophoresis in starch gels. PZP is a prominent constituent of late-pregnancy sera. In healthy, nonpregnant females and in males, PZP is present in trace amounts only: females, 10 to 30 mg/L; males, less than 10 mg/L. During pregnancy, PZP levels may reach 1000 to 1400 mg/L just before term. Sottrup-Jensen et al. (1984) showed that PZP closely resembles alpha-2-macroglobulin in structure. Both have a quaternary structure of 2 covalently bound 180-kDa subunits which are further noncovalently assembled into a tetramer of 720 kDa. Amino acid sequence of the 2 proteins are extensively homologous.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: PZP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human