Polyclonal Antibody to Interleukin 11 Receptor Alpha (IL11Ra), derived from recombinant IL11Ra (Asn194~Gln329), is reactive with Mouse/Human/Rat.
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IL-11 receptor is a member of the hematopoietic cytokine receptor family. This particular receptor is very similar to ciliary neurotrophic factor, since both contain an extracellular region with a 2-domain structure composed of an immunoglobulin-like domain and a cytokine receptor-like domain. Alternative splicing has been observed at this locus and two variants, each encoding a distinct isoform, have been identified. This receptor was found to be a 422-amino acid protein containing a signal peptide followed by extracellular, transmembrane, and cytoplasmic domains. The extracellular region has a 2-domain structure homologous to those of the receptors for IL6R and ciliary neurotrophic factor (CNTFR), an immunoglobulin-like domain and a cytokine receptor-like domain.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: IL11Ra
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse;Human;Rat