Anti-CDKN1A Rabbit Polyclonal Antibody

Supplier: CLOUD-CLONE CORP MS
PAE624MU01
MSPP-PAE624MU1EA 360 USD
MSPP-PAE624MU1
Anti-CDKN1A Rabbit Polyclonal Antibody
Antibodies
Polyclonal antibody to Cyclin Dependent Kinase Inhibitor 1A (CDKN1A), derived from recombinant CDKN1A(Ser2~Pro159), is reactive with Mouse.

  • High specificity, affinity and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
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The p21 (WAF1) protein binds to and inhibits the activity of cyclin-CDK2 or -CDK4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53-dependent cell cycle G1 phase arrest in response to a variety of stress stimuli.,In addition to growth arrest, p21 can mediate cellular senescence and one of the ways it was discovered was as a senescent cell-derived inhibitor. The p21(WAF1) protein can also interact with proliferating cell nuclear antigen (PCNA), a DNA polymerase accessory factor, and plays a regulatory role in S phase DNA replication and DNA damage repair.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: CDKN1A
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse
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