Anti-NIS Rabbit Polyclonal Antibody

Supplier: CLOUD-CLONE CORP MS
PAE385HU01
MSPP-PAE385HU1EA 350 USD
MSPP-PAE385HU1
Anti-NIS Rabbit Polyclonal Antibody
Antibodies
Polyclonal Antibody to Sodium Iodide Symporter (NIS), derived from recombinant NIS (Ser547~Leu643), is reactive with Human.

  • High specificity, affinity, and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
  • All in stock and fast global delivery
  • 100% Quality and service satisfaction guarantee

The sodium-iodide symporter (NIS) is an ion pump that actively transports iodide (I-) across the basolateral membrane into thyroid epithelial cells. The NIS a member of the sodium/solute symporter family. Active transport of iodine into the thyroid gland is an important step in the process of iodide organification and the formation of triiodothyronine (T3) and thyroxine (T4). The symporter is stimulated by TSH, thereby increasing iodine uptake and iodination of tyrosine. The pump symports two sodium ions for every iodide ion. This symporter is driven by low internal sodium concentration in the thyroid epithelial cells, via facilitated diffusion, caused by the sodium/potassium ATPase pump.This pump is the target of certain anion based inhibitors such as perchlorate, pertechnetate, and thiocyanate.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please properly store each component based on the instruction.

Type: Primary
Antigen: NIS
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human
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