Anti-HPD Rabbit Polyclonal Antibody

Supplier: CLOUD-CLONE CORP MS
PAE251HU01
MSPP-PAE251HU1EA 350 USD
MSPP-PAE251HU1
Anti-HPD Rabbit Polyclonal Antibody
Antibodies
Polyclonal antibody to 4-Hydroxyphenylpyruvate Dioxygenase (HPD), derived from recombinant HPD(Thr2~Met393), is reactive with Human/Mouse/Rat/Pig.

  • High specificity, affinity and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
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4-Hydroxyphenylpyruvate dioxygenase HPPD is an Fe-containing enzyme, that catalyzes the second reaction in the catabolism of tyrosine - the conversion of 4-hydroxyphenylpyruvate to homogentisate.The mechanism of action of 4-hydroxyphenylpyruvate dioxygenase involves a decarboxylation step and an oxidation step, followed by a rearrangement step to form homogentisic acid. The HPPD reaction occurs through a NIH shift and involves the oxidative decarboxylation of an α-oxo acid as well as aromatic ring hydroxylation. The NIH-shift, which has been demonstrated through isotope-labeling studies, involves migration of an alkyl group to form a more stable carbocation. The shift, accounts for the observation that C3 is bonded to C4 in 4-hydroxyphenylpyruvate but to C5 in homogentisate.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: HPD
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Pig
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