Polyclonal Antibody to Thyroid Stimulating Hormone Receptor (TSHR), derived from recombinant TSHR (Pro28~Gly245), is reactive with Rat/Human/Mouse.
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The thyrotropin receptor is a protein responds to thyroid-stimulating hormone (also known as 'thyrotropin', and stimulates the production of thyroxine (T4) and triiodothyronine (T3). The TSH receptor is a member of the G-protein coupled receptor superfamily of integral membrane proteins.It is primarily found on the surface of the thyroid epithelial cells. It should not be confused with 'thyrotropin-releasing hormone' (TRH) or 'thyrotropin-releasing hormone receptor' (TRHR). The deduced 764-amino acid protein has a molecular mass of 86.8 kD and contains a signal peptide, 7 transmembrane regions, 5 potential glycosylation sites, and a short intracytoplasmic region. The TSHR cDNA encoded a functional receptor that activated adenylate cyclase in response to TSH.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please properly store each component based on the instruction.
Type: Primary
Antigen: TSHR
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat, Human, Mouse