Polyclonal Antibody to Regucalcin (RGN), derived from recombinant RGN (Gln65~Gly299), is reactive with Human/Mouse/Rat.
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Regucalcinis a highly conserved, calcium-binding protein, that is preferentially expressed in the liver and kidney. It may have an important role in calcium homeostasis. Studies in rat indicate that this protein may also play a role in aging, as it shows age-associated down-regulation. This gene is part of a gene cluster on chromosome Xp11.3-Xp11.23. Alternative splicing results in two transcript variants having different 5' UTRs, but encoding the same protein. Regucalcin is a proposed name for a calcium-binding protein that was discovered in 1978. Regucalcin differs from calmodulin and other Ca²⁺-related proteins as it does not contain an EF-hand motif of Ca²⁺-binding domain. It may regulate the effect of Ca²⁺ on liver cell functions.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: RGN
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat