Anti-FPN Rabbit Polyclonal Antibody

Supplier: CLOUD-CLONE CORP MS
PAC489MU01
MSPP-PAC489MU1EA 360 USD
MSPP-PAC489MU1
Anti-FPN Rabbit Polyclonal Antibody
Antibodies
Polyclonal antibody to Ferroportin (FPN), derived from recombinant FPN, is reactive with Mouse.

  • High specificity, affinity and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
  • All in stock and fast global delivery
  • 100% Quality and service satisfaction guarantee!

Ferroportin is a transmembrane protein that transports iron from the inside of a cell to the outside of it. Recent research suggests that ferroportin is inhibited by hepcidin, which therefore is the 'master regulator' of human iron metabolism. Hepcidin binds to ferroportin, and results in the internalisation of ferroportin within the cell, followed by degradation by the proteasome. This results in retention of iron within the cell, and a reduction in iron levels within the plasma. This is part of the mechanism that causes anaemia of chronic disease, hepcidin is released from the liver in response to inflammatory cytokines, namely interleukin-6, which results in an increased hepcidin concentration and a consequent decrease in plasma iron levels.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: FPN
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse
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