Anti-CFB Rabbit Polyclonal Antibody

Supplier: CLOUD-CLONE CORP MS
PAC011MU02
MSPP-PAC011MU2EA 360 USD
MSPP-PAC011MU2
Anti-CFB Rabbit Polyclonal Antibody
Antibodies
Polyclonal Antibody to Complement Factor B (CFB), derived from recombinant CFB (Leu474~Arg590), is reactive with Mouse/Rat.

  • High specificity, affinity, and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
  • All in stock and fast global delivery
  • 100% Quality and service satisfaction guarantee

Complement factor B is a a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please properly store each component based on the instruction.

Type: Primary
Antigen: CFB
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse, Rat
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