Polyclonal Antibody to Cluster Of Differentiation (CD163), derived from recombinant CD163(Leu719~Thr1029), is reactive with Human.
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CD163, a hemoglobin scavenger receptor, is expressed in monocytes and macrophages.Acute phase-regulated receptor involved in clearance and endocytosis of hemoglobin/haptoglobin c by macrophages and may thereby protect tissues from free hemoglobin-mediated oxidative damage.,CD163 may play a role in the uptake and recycling of iron, via endocytosis of hemoglobin/haptoglobin and subsequent breakdown of heme. It binds hemoglobin/haptoglobin complexes in a calcium-dependent and pH-dependent manner. It exhibits a higher affinity for complexes of hemoglobin and multimeric haptoglobin of HP*1F phenotype than for complexes of hemoglobin and dimeric haptoglobin of HP*1S phenotype.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: CD163
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human