Polyclonal Antibody to Programmed Cell Death Protein 6 Interacting Protein (PDCD6IP), derived from recombinant PDCD6IP(Glu174~Val383), is reactive with Human/Mouse/Rat.
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Programmed cell death 6-interacting protein is a protein thought to participate in programmed cell death. Studies using mouse cells have shown that overexpression of this protein can block apoptosis. In addition, the product of this gene binds to the product of the PDCD6 gene, a protein required for apoptosis, in a calcium-dependent manner.,This gene product also binds to endophilins, proteins that regulate membrane shape during endocytosis. Overexpression of this gene product and endophilins results in cytoplasmic vacuolization which may be partly responsible for the protection against cell death.Several alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: PDCD6IP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human;Mouse;Rat