Anti-TXNIP Rabbit Polyclonal Antibody

Supplier: CLOUD-CLONE CORP MS
PAB162HU01
MSPP-PAB162HU1EA 332 USD
MSPP-PAB162HU1
Anti-TXNIP Rabbit Polyclonal Antibody
Antibodies
Polyclonal Antibody to Thioredoxin-interacting Protein (TXNIP), derived from recombinant TXNIP (Ile32~Ala367), is reactive with Human/Rat/Pig.

  • High specificity, affinity, and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
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Exposure to vitamin D3 (1,25-dihydroxyvitamin D3) or phorbol ester induces the bipotent HL-60 cell promyelocytic leukemia cell line to differentiate into monocytes/macrophages, whereas retinoic acid and dimethylsulfoxide induce differentiation towards granulocytes. The differentiation is accompanied by regulation of MYC, FOS, FMS (CSF1R), and myeloblastin (PRTN3;). By differential screening of HL60 cell lines, Chen and DeLuca (1994) identified a cDNA encoding TXNIP, which they termed VDUP1. The deduced TXNIP protein has 391 amino acids. Ribonuclease protection analysis showed dramatically increased expression of TXNIP in response to vitamin D3 but not to phorbol ester. Chen and DeLuca (1994) concluded that TXNIP is not involved in the differentiation process.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: TXNIP
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human;Rat;Pig
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