Anti-PDL2 Rabbit Polyclonal Antibody

Supplier: CLOUD-CLONE CORP MS
PAA789RA01
MSPP-PAA789RA1EA 342 USD
MSPP-PAA789RA1
Anti-PDL2 Rabbit Polyclonal Antibody
Antibodies
Polyclonal Antibody to Programmed Cell Death Protein 1 Ligand 2 (PDL2), derived from recombinant PDL2 (Phe21~Gln268), is reactive with Rat.

  • High specificity, affinity, and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
  • All in stock and fast global delivery
  • 100% Quality and service satisfaction guarantee

Using flow cytometric analysis, Latchman et al. (2001) showed that the IgV region of mouse Pdl2, like Pdl1, binds to human PDCD1 but not to CTLA4, CD28, or ICOS. Stimulation of mouse T cells with anti-CD3 and Pdl2 or Pdl1 resulted in inhibition of proliferation and cytokine production, and Pdl2 could inhibit T-cell receptor -CD28 signals at low antigen concentrations. Latchman et al. (2001) proposed that blocking of the PDL-PDCD1 pathway may enhance antitumor immunity, whereas stimulating this pathway may help downregulate graft rejection and autoimmune and allergic reactions., Latchman et al. (2001) mapped the PDL2 gene to chromosome 9p24.2, in close proximity to the PDL1 gene. Tseng et al. (2001) mapped the mouse Pdl2 gene to chromosome 19C2-C3.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: PDL2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Rat
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