Polyclonal Antibody to Collagen Type IV Alpha 1 (COL4a1), derived from recombinant COL4a1 (Pro1416~Thr1669), is reactive with Mouse.
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Collagen, type IV, alpha 1 is a major type IV alpha collagen chain of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene so that each gene pair shares a common promoter. Types I, II, and III collagen, the so-called interstitial collagens, are in many ways distinct from basement membrane collagen. Type IV collagen does not form ordered fibrillar structures; rather, a meshwork is formed by 4 molecules held together at the ends. Both disulfide and typical lysyl-derived collagen crosslinks are involved. The collagen IV molecule is a heterotrimer of 2 alpha-1 chains and 1 alpha-2 chain. The alpha-2 chain is encoded at a distinct locus (COL4A2).
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: COL4a1
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Mouse