Polyclonal Antibody to Intercellular Adhesion Molecule 5 (ICAM5), derived from recombinant ICAM5 (Arg409~Pro674), is reactive with Human/Mouse/Pig.
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Intercellular adhesion molecule 5 is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is expressed on the surface of telencephalic neurons and displays two types of adhesion activity, homophilic binding between neurons and heterophilic binding between neurons and leukocytes. It may be a critical component in neuron-microglial cell interactions in the course of normal development or as part of neurodegenerative diseases.The 924-amino acid polypeptide comprises an N-terminal signal peptide, an extracellular region with 9 Ig-like domains, a single transmembrane region, and a C-terminal cytoplasmic tail.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: ICAM5
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human;Mouse;Pig