Monoclonal Antibody to Apolipoprotein B (APOB), derived from recombinant APOB (H+Phe2747~Leu2913), is reactive with Rat/Human/Mouse/Pig.
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Apolipoprotein B (APOB) is the primary apolipoprotein of low-density lipoproteins (LDL or 'bad cholesterol'), which is responsible for carrying cholesterol to tissues. While it is unclear exactly what functional role APOB plays in LDL, it is the primary apolipoprotein component and is absolutely required for its formation. What is clear is that the APOB on the LDL particle acts as a ligand for LDL receptors in various cells throughout the body., Through a mechanism that is not fully understood, high levels of APOB can lead to plaques that cause vascular disease (atherosclerosis), leading to heart disease. There is considerable evidence that levels of APOB are a better indicator of heart disease risk than total cholesterol or LDL.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: APOB
Clonality: Monoclonal
Clone: C3
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG2a kappa
Reactivity: Rat;Human;Mouse;Pig