Anti-TGFb1 Mouse Monoclonal Antibody [clone: A1]

Supplier: CLOUD-CLONE CORP MS
MAA124HU22
MSPP-MAA124HU2EA 290 USD
MSPP-MAA124HU2
Anti-TGFb1 Mouse Monoclonal Antibody [clone: A1]
Antibodies
Monoclonal Antibody to Transforming Growth Factor Beta 1 (TGFb1), derived from recombinant TGFb1 (Ala279~Ser390), is reactive with Human/Mouse/Rat.

  • High specificity, affinity and purity
  • Extensive validation and batch-to-batch consistency
  • Diverse range of conjugated and custom options
  • Comprehensive validation data and documentation
  • All in stock and fast global delivery
  • 100% Quality and service satisfaction guarantee

TGF-β is capable of producing a variety of effects and virtually all cell types respond to this factor in some way. The inappropriate presence of active TGF-β1 has been implicated in a variety of pathological conditions Because of the necessity for regulating its activity tightly, TGF-β is secreted by cells in the form of an inactive complex. This complex consists of TGF-β1 associated non-covalently with a protein designated the latency associated peptide (LAP). TGF-β1 and LAP represent components of a pro-peptide that is cleaved in a post-golgi compartment prior to secretion. LAP and TGF-β1 each consist of a disulfide-linked homodimer and the association of these two components renders TGF-β1 inactive and inaccessible to anti-TGF-β antibodies.

Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.

Type: Primary
Antigen: TGFb1
Clonality: Monoclonal
Clone: A1
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 Kappa
Reactivity: Human, Mouse, Rat
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