Monoclonal Antibody to Interleukin 17 (IL17), derived from recombinant IL17 (Val21~Ala153), is reactive with Rabbit.
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Interleukin 17 (IL-17; also known as IL-17A) is a 30 to 35 kDa variably glycosylated homodimeric protein that belongs to a unique family of cysteine-knot related proteins. Its sequence was originally isolated from an activated rodent hybridoma and termed CTLA-8. It is synthesized as a 155 amino acid (aa) precursor that contains a 23 aa signal sequence and a 15 kDa, 132 aa mature segment. Although there are two intrachain disulfide bonds that create a ring reminiscent of those found in cysteine-knot proteins, the actual closed knot structure does not appear to form. IL-17 has one potential N-linked glycosylation site. IL-17, a T cell-derived proinf lammatory cytokine, is produced by TCRα/β+CD4-CD8- thymocytes, as well as by activated CD4+ and CD4+CD45RO+ memory T cells.
Caution: For research use only. Not for use in clinical diagnostic procedures. Please proper stored each component based on the instruction.
Type: Primary
Antigen: IL17
Clonality: Monoclonal
Clone: 6#
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1 kappa
Reactivity: Rabbit