Biotin-Linked Monoclonal Antibody to Lectin Galactoside Binding, Soluble 3 Binding Protein (LGALS3BP), derived from recombinant LGALS3BP (Met24~Leu221), is reactive with Human.
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Galectin-3-binding protein is a protein encoded by the LGALS3BP gene.The galectins are a family of beta-galactoside-binding proteins implicated in modulating cell-cell and cell-matrix interactions. LGALS3BP has been found elevated in the serum of patients with cancer and in those infected by the human immunodeficiency virus (HIV). It appears to be implicated in immune response associated with natural killer (NK) and lymphokine-activated killer (LAK) cell cytotoxicity. Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25. The native protein binds specifically to a human macrophage-associated lectin known as Mac-2 and also binds galectin 1.
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Type: Primary
Antigen: LGALS3BP
Clonality: Monoclonal
Clone: D3
Conjugation: Biotin
Epitope:
Host: Mouse
Isotype: IgG2b Kappa
Reactivity: Human