Anti-SV40 T Antigen (Ab-2) Mouse Monoclonal Antibody [clone: PAb416]

Supplier: MilliporeSigma
DP02-200UG
EMDP02-200UGEA 730.1 USD
EMDP02-200UG
Anti-SV40 T Antigen (Ab-2) Mouse Monoclonal Antibody [clone: PAb416]
Antibodies
SV40 T Ag (Ab-2) is a mouse monoclonal antibody with specificity for antigenic determinants unique to the SV40 large T antigen and non-reactive with SV40 small T antigen. Both antigens are encoded by the early region of the SV40 genome. The large T antigen binds DNA, and complexes with a 53,000 dalton cellular transforming protein, p53, which is required for initiation of viral DNA replication during lytic growth. In addition the large T antigen binds DNA polymerase and the transcription factor AP-2 and forms a specific complex with the p105 product of the retinoblastoma susceptibility gene.

Type: Primary
Antigen: SV40 T Antigen (Ab-2)
Clonality: Monoclonal
Clone: PAb416
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2a
Reactivity: SV4-infected cells
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