Necrostatin-1
Supplier: Thermo Scientific Chemicals
Synonyms:
5-((1H-Indol-3-yl)methyl)-3-methyl-2-thioxoimidazolidin-4-one, Nec-1
Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.
- Yellow Powder
- Cell-permeable, potent, and selective blocker of necroptosis
Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.
Formula:
C₁₃H₁₃N₃OS MW: 259.327 g/mol Storage Temperature: Refrigerator |
MDL Number:
MFCD00056916 CAS Number: 4311-88-0 |
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