Necrostatin-1

Supplier: Thermo Scientific Chemicals

Synonyms: 5-((1H-Indol-3-yl)methyl)-3-methyl-2-thioxoimidazolidin-4-one, Nec-1

J65341-FPL
AAJ65341-FPLEA 135 USD
AAJ65341-FPL
Necrostatin-1
Necrostatin-1

Necrostatin-1 functions as an allosteric inhibitor of the death domain receptor-associated adaptor kinase RIP (RIP1) in the necroptosis pathway. While affecting this distinct cell death pathway, Necrostatin-1 does not present any perturbation of the Fas/TNFR triggered canonical apoptosis cascade.


  • Yellow Powder
  • Cell-permeable, potent, and selective blocker of necroptosis


Light sensitive. Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents, heat, light. Store in refrigerator.

Formula: C₁₃H₁₃N₃OS
MW: 259.327 g/mol
Storage Temperature: Refrigerator
MDL Number: MFCD00056916
CAS Number: 4311-88-0

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