Anti-CDT1 / DUP Goat Polyclonal Antibody

Supplier: Genetex
GTX14676
89367-378EA 628.09 USD
89367-378
Anti-CDT1 / DUP Goat Polyclonal Antibody
Antibodies
Geminin is a protein that inhibits DNA replication by preventing the loading of MCM complex on chromatin. Human CDT1 is a 65kDa protein that contains 546 amino acids and coimmunoprecipitates with Geminin. Inhibition of DNA replication by Geminin in cell-free cDNA replication extracts can be reversed by the addition of excess CDT1. In the normal cell cycle, CDT1 is present only in G1 and S phases, whereas Geminin is present in S and G2 phases. Wohlschlegel et al. (2000) concluded that their results suggest that Geminin inhibits inappropriate origin firing by targeting CDT1.

Approx 60kDa band observed in Human Ovary lysates (calculated MW of 60.4kDa according to NP_112190.2). Recommended concentration: 1-3µg/ml.

Type: Primary
Antigen: CDT1 / DUP
Clonality: Polyclonal
Clone: 0
Conjugation: Unconjugated
Epitope:
Host: Goat
Isotype: IgG
Reactivity:
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