Alsterpaullone ≥95%

Supplier: Enzo Life Sciences

Synonyms: 7,12-Dihydro-9-nitroindolo[3,2-d][1]benzazepin-6(5H)-one

270-275-M005
89147-536EA 96 USD
89147-536 89147-538
Alsterpaullone ≥95%
Alsterpaullone

Inhibitor of CDK and GSK


Potent inhibitor of CDK1/cyclin B (IC50=35nM). Potent and selective inhibitor of CDK2/cyclin A, CDK2/cyclin E (IC50=200nM), CDK5/p25 (IC50=40nM), CDK5/p35 (IC50=40nM) and GSK-3β . Induces apoptosis by activation of caspase-8 and caspase-9 followed by disruption of the mitochondrial potential.Licensed from NCI.

Formula: C₁₆H₁₁N₃O₃
MW: 293.3 g/mol
MDL Number: MFCD02683579
CAS Number: 237430-03-4
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