Diptheria Toxin, MilliporeSigma
Supplier: MilliporeSigma
322326-1MG
80055-232EA
1459.19
USD
80055-232
Diptheria Toxin, MilliporeSigma
Microbiology Test Systems
Antigen-Antibody Tests
Ag-AK, Seren
Diphtheria toxin Catalyzes ADP-ribosylation of eukaryotic aminoacyltransferase II (EF2) using NAD as substrate, thereby inhibiting protein synthesis
- Induce internucleosomal breakdown
- It can cause DNA fragmentation and cytolysis in U937 cells
- Activation requires nicking with a protease followed by reduction with DTT
- Storage: +2 °C...+8 °C
For assays employing very low concentrations of diphtheria toxin, the use of a carrier protein, such as BSA or HSA, is recommended.The primary target is Eukaryotic aminoacyltransferase II (EF2)
This toxin is from Corynebacterium diphtheriae. This toxin is highly harmful
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