Pseudouridine-5-Triphosphate (Pseudo-UTP)
Supplier: New England Biolabs (NEB)
mRNA has emerged as a potent modality for therapeutics.
Supplied as sodium salts, pH 7.0
- Modified NTPs are commonly used for reduction of immunogenicity for in vitro transcription RNA
- No detectable RNase, DNase, phosphatase or protease contaminating activities
- ≥95% purity, as determined by HPLC
- Optimal activity and stability for up to 24 months
Incorporation of chemically modified ribonucleotides improves the efficacy of these therapies by increasing stability, reducing immunogenicity, and enhancing translatability of mRNAs.
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