Anti-TLR4 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

PAB Rabbit TLR4 Human IgG 25 µl F/ELISA

PAB Rabbit TLR4 Human IgG 25 µl F/ELISA

600-401-MK3 600-401-MK3S

76309-356EA 551.64 USD

76309-356 76309-358

Anti-TLR4 Rabbit Polyclonal Antibody

Antibodies

TLR4 (Toll-Like Receptor 4). Toll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kB. Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis. Mutations in this gene have been associated with differences in LPS responsiveness, macular degeneration, and pertussis. Anti-TLR4 Antibody is useful for researchers interested in transcription factor research, cytokine research, MIF action through Endocytic Pathway, and rheumatoid arthritis.

Type: Primary
Antigen: TLR4
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype:
Reactivity: Human

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