AccuSignal Nitrotyrosine ELISA Kit, Rockland Immunochemicals

Supplier: Rockland Immunochemical

KOA0888
76236-380EA 672.84 USD
76236-380
AccuSignal Nitrotyrosine ELISA Kit, Rockland Immunochemicals
Assays ELISAs

AccuSignal Nitrotyrosine ELISA Kit


  • Colorimetric Competitive ELISA (Enzyme-linked Immunosorbent Assay)
  • Sensitivity: 50nM. Range: 62.5-8000nM.


Nitrotyrosine has been identified as a marker of inflammation and NO production. Nitrotyrosine is formed in presence of the active metabolite NO. Various pathways including the formation of peroxinitrite lead to nitrotyrosine production. Since nitrotyrosine is a stable end product of peroxynitrite oxidation, assessment of its plasma concentration may be useful as a marker of NO-dependent damage in vivo. Since NOX is only an indicator for enhanced NO production, protein associated nitrotyrosine might be a more suitable marker for damage induced by reactive nitrogen intermediates derived from NO. Furthermore, most proteins have a longer half life in the circulation than NOX levels. The presence of nitrotyrosine has been detected in various inflammatory processes including atherosclerotic plaques, celiac disease, rheumatoid arthritis, chronic renal failure and septic shock. In normal plasma low, undetectable, levels of nitrotyrosine are present. Nitrosylation of the amino acid tyrosine occurs both for free tyrosine and for protein bound tyrosine.


Colorimetric Competitive ELISA (Enzyme-linked Immunosorbent Assay) assay for quantification of Free Nitrotyrosine in Cell lysates, Plasma, Serum, and Urine. Sensitivity: 50nM. Range: 62.5-8000nM.

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