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Anti-VWF Mouse Monoclonal Antibody [clone: F8/86]

Supplier: Prosci

33-608

76194-454EA 738.11 USD

76194-454

Anti-VWF Mouse Monoclonal Antibody [clone: F8/86]

Antibodies

von Willebrand Factor (vWF) is a multimeric glycoprotein that is found in endothelial cells, plasma and platelets. It acts as a carrier protein for Factor VIII and promotes platelet adhesion and aggregation. vWF undergoes a variety of posttranslational modifications that influence the affinity and availability for Factor VIII, including cleavage of the propeptide and formation of N-terminal disulfide bonds. This antibody helps to establish the endothelial nature of some lesions of disputed histogenesis, e.g. Kaposi's sarcoma and cardiac myxoma. It is widely used for differentiating vascular lesions from those of other tissue differentiation within a panel of other vascular markers although not all tumors of endothelial differentiation contain this antigen.

Flow Cytometry: 0.5-1 ug/million cells in 0.1ml Immunofluorescence: 0.5-1 ug/ml Immunohistochemistry (FFPE): 1-2 ug/ml for 30 minutes at RT The optimal dilution of the von Willebrand Factor antibody for each application should be determined by the researcher.

Type: Primary
Antigen: VWF
Clonality: Monoclonal
Clone: F8/86
Conjugation: Unconjugated
Epitope:
Host: Mouse
Isotype: IgG1, kappa
Reactivity: Human

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