Anti-RSAD2 Rabbit Polyclonal Antibody

Supplier: Prosci

33-037

76194-032EA 646.24 USD

76194-032

Anti-RSAD2 Rabbit Polyclonal Antibody

Antibodies

Viral infection induces the interferon (IFN) response which triggers the production of an array of anti-viral proteins. Viperin (Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible) is expressed in response to IFN-b binding to the IFN receptor, inducing the formation of the IFN-stimulated gene factor 3 complex which then binds to the Viperin promoter. It inhibits many DNA and RNA viruses through a diverse range of mechanisms and is involved in the PRR-mediated innate immune response. Viperin has been shown to be produced in response to TLR3 and TLR4 activation, but not TLR2 and TLR5. It may be involved in the TLR7 and TLR9-induced production of type I IFN by plasmacytoid dendritic cells (pDCs).

Western blot: 3-6 ug/ml Provided assay concentrations are suggestions only, Viperin antibody titration may be required for optimal results.

Type: Primary
Antigen: RSAD2
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: IgG
Reactivity: Human, Mouse, Rat, Dog

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