Anti-PCDHB12 Rabbit Polyclonal Antibody

Supplier: Prosci

Western blot analysis in NCI-H292 cell line lysates (35 µg/lane)

PCDHB12 Antibdy immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining This data demonstrates the use of PCDHB12 Antibdy for immunohistochemistry

Western blot analysis in NCI-H292 cell line lysates (35 µg/lane)

PCDHB12 Antibdy immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining This data demonstrates the use of PCDHB12 Antibdy for immunohistochemistry

56-353

76011-808EA 640.99 USD

76011-808

Anti-PCDHB12 Rabbit Polyclonal Antibody

Antibodies

This gene is a member of the protocadherin beta gene cluster, one of three related gene clusters tandemly linked on chromosome five. The gene clusters demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The beta cluster contains 16 genes and 3 pseudogenes, each encoding 6 extracellular cadherin domains and a cytoplasmic tail that deviates from others in the cadherin superfamily. The extracellular domains interact in a homophilic manner to specify differential cell-cell connections. Unlike the alpha and gamma clusters, the transcripts from these genes are made up of only one large exon, not sharing common 3' exons as expected. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins. Their specific functions are unknown but they most likely play a critical role in the establishment and function of specific cell-cell neural connections.

For WB starting dilution is: 1:1000 For IHC-P starting dilution is: 1:10~50

Type: Primary
Antigen: PCDHB12
Clonality: Polyclonal
Clone:
Conjugation: Unconjugated
Epitope:
Host: Rabbit
Isotype: Rabbit Ig
Reactivity: Human

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