Anti-Rabies Mouse Monoclonal Antibody (CF488A) [clone: Rab-50]

Supplier: Biotium

BNC880943-100 BNC880943-500
75973-616EA 205.77 USD
75973-616 75973-618
Anti-Rabies Mouse Monoclonal Antibody (CF488A) [clone: Rab-50]
Antibodies
This antibody recognizes viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore. This MAb is useful in detecting rabies virus by ELISA and Western. It is capable of neutralizing rabies virus. Rabies virus (Neurotropic virus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumb like glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Lipid solvents destroy virus infectivity. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.

CF® dyes are Biotium's next-generation fluorescent dyes. CF®488A is a green fluorescent dye (Ex/Em 490/515 nm) with excellent brightness and photostability. The dye is minimally charged for less non-specific binding. CF®488A also is compatible with super-resolution imaging by TIRF.

Type: Primary
Antigen: Not Applicable
Clonality: Monoclonal
Clone: Clone Rab-50
Conjugation: CF488A
Epitope:
Host: Mouse
Isotype: IgG2b kappa
Reactivity: Rabies
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