STK11

Supplier: Rockland Immunochemical

009-001-T60S

75935-408EA 388.66 USD

75935-408 75935-410

STK11

Proteins and Peptides

STK11 control protein-GST fusion

Control Protein
PCA Assays
ImmunoBlot

LKB1 (STK11) is a member of the serine/threonine kinase family which regulates cell polarity and functions as a tumor suppressor. STK11 is a critical barrier to pulmonary tumorigenesis which controlling initiation, differentiation, and metastasis. STK11 plays a central role in restricting HSC entry into cell cycle and in broadly maintaining energy homeostasis in hematopoietic cells through a novel metabolic checkpoint (1). STK11 serves as an essential regulator of HSCs and hematopoiesis, and more generally, points to the critical importance of coupling energy metabolism and stem cell homeostasis (2). SKT11 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, Apoptosis/Autophagy, Cancer, Cellular Stress, Metabolic Disorder, and Ser/Thr Kinases research.

STK11 Protein is stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. STK11 Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~85kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

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