Anti-STIM2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

600-401-H21

75935-404EA 635.22 USD

75935-404

Anti-STIM2 Rabbit Polyclonal Antibody

Antibodies

STIM2 antibody detects human STIM2. In T lymphocytes, the sole pathway for Ca++ entry following antigen-receptor binding is through store-operated Ca++-release-activated Ca++ (CRAC) channels. These channels are made up of the pore-forming subunit ORAI1 and the stromal interaction molecule 1 (STIM1), a protein that functions as a Ca++ sensor and activates the CRAC channels, migrating to the plasma membrane from endoplasmic reticulum (ER)-like sites which act as the Ca++ store. A related molecule, STIM2, acts to inhibit the STIM1-mediated store-operated Ca++ entry, and can form complexes with STIM1, suggesting they may play a coordinated role in controlling Ca++ entry. At least three isoforms of STIM2 are known to exist. This STIM2 antibody is predicted to have no cross-reactivity to STIM1. Anti-STIM2 is ideal for investigators involved enzyme research.

Anti-STIM2 Antibody is suitable for use in E,WB, and IHC. Expect a band approximately ~83.9 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Type: Primary
Antigen: STIM2
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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