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Anti-TOLLIP Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

PAB Rabbit TOLLIP Human MS Rat IgG 100 µg

PAB Rabbit TOLLIP Human MS Rat IgG 100 µg

600-401-FL7

75933-012EA 635.22 USD

75933-012

Anti-TOLLIP Rabbit Polyclonal Antibody

Antibodies

Toll-like receptors (TLRs) are evolutionarily conserved pattern-recognition molecules resembling the toll proteins that mediate antimicrobial responses in Drosophila. These proteins recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses. The TLRs act through adaptor molecules to activate various kinases and transcription factors so the organism can respond to potential infection. These adaptor molecules include TOLLIP, MyD88, and TRIF. TOLLIP associates directly with TLR2 and TLR 4, acting as an inhibitor to TLR activation. This negative regulation of TLR signaling may serve to limit the production of proinflammatory mediators during infection and inflammation.

Anti-TOLLIP Antibody has been tested for use in ELISA, Western Blotting, Immunocytochemistry. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 30 kDa in Western Blots of specific cell lysates and tissues.

Type: Primary
Antigen: TOLLIP
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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