Anti-TET2 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

PAB Rabbit TET2 Human Mouse IgG 100 µg

PAB Rabbit TET2 Human Mouse IgG 100 µg

600-401-FC9

75932-830EA 635.22 USD

75932-830

Anti-TET2 Rabbit Polyclonal Antibody

Antibodies

TET2, a member of the ten-eleven-translocation (TET) family of genes, is a methylcytosine dioxygenase that catalyzes the conversion of methylcytosine to 5-hydroxymethylcytosine. It is a candidate tumor suppressor gene reported to be mutated in approximately 14% of patients with JAK2V617F-positive myeloproliferative neoplasms (1), and can be mutated in other hematopoietic disorders such as myelodysplastic syndromes, acute myeloid leukemia, and chronic myelomonocytic leukemia (2). Analysis of the TET2 and JAK2 mutations in these neoplasms suggests that mutations in TET2 do not represent a predisposition for acquiring mutations in JAK2.

Anti-TET2 Antibody has been tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 224 kDa in Western Blots of specific cell lysates and tissues.

Type: Primary
Antigen: TET2
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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