Anti-TASK1 Mouse Monoclonal Antibody [Clone: S374-48]

Supplier: Rockland Immunochemical
200-301-W85
75932-580EA 565.22 USD
75932-580
Anti-TASK1 Mouse Monoclonal Antibody [Clone: S374-48]
Antibodies
K+ channels are divided into three subclasses reflecting the number of transmembrane segments (TMS), which are designated 6TMS, 4TMS and 2TMS. Members of the 4TMS class contain two distinct pore regions and include TWIK, TREK, TRAAK and TASK. TASK channels are highly sensitive to external pH in the physiological range. TASK-1 is expressed in brain and in rat heart, with high levels of expression in the right atrium. TASK-2, mainly expressed in kidney, is localized in cortical distal tubules and collecting ducts, suggesting a role in renal K+ transport. TASK-3 from rat cerebellum shares 54% identity with TASK-1, but less than 30% identity with TASK-2 and other tandem pore K+ channels. Anti-TASK1 Potassium Channel Antibody is ideal for research in Neuroscience, particularly studies concerning the dopaminergic neuron and melatonin signaling.

Anti-TASK1 Potassium Channel Antibody is suitable for Western Blots, Immunohistochemistry and Immunocytochemistry. Expect a band approximately ~50kDa on specific lysates or tissues. Does not cross react with TASK3. Specific conditions for reactivity should be optimized by the end user.

Type: Primary
Antigen: TASK1
Clonality: Monoclonal
Clone: S374-48
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG2b
Reactivity:
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