Anti-MAP3K7 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

PAB Rabbit TAK1 HU Mouse Rat IgG 100 µg

PAB Rabbit TAK1 HU Mouse Rat IgG 100 µg

600-401-EZ6

75932-566EA 635.22 USD

75932-566

Anti-MAP3K7 Rabbit Polyclonal Antibody

Antibodies

TAK1 (TGF-beta activated protein kinase 1) is a widely expressed enzyme originally identified as a mitogen-activated protein kinase kinase kinase (MAP3K7). It has since been shown to mediate various intracellular signaling pathways, such as those induced by TGF-beta and members of the Toll-IL-1R (TIR) superfamily, thus acting as an intermediate in both proliferative and innate and adaptive immune responses. TAK1 is normally present in cells in a complex with TAK1-binding protein 1 (TAB1) and either TAB2 or TAB3. Association with TAB1 triggers TAK1 kinase activity by inducing TAK1 autophosphorylation, while TAB2 and possibly TAB3 may contribute to SAPK2a/p38a-mediated feedback inhibition of TAK1 activity.

Anti-TAK1 Antibody has been tested for use in ELISA, Western Blotting and Immunofluorescence. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 67 kDa in Western Blots of specific cell lysates and tissues.

Type: Primary
Antigen: MAP3K7
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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