STMN1

Supplier: Rockland Immunochemical

009-001-T58S
75932-226EA 380.3 USD
75932-226 75932-228
STMN1
Proteins and Peptides

Stathmin control protein-HIS Epitope


  • Control Protein
  • PCA Assays
  • ImmunoBlot


Stathmin is a ubiquitous, highly conserved protein present in the cytoplasm in a variety of unphosphorylated and phosphorylated forms. Stathmin functions as an intracellular relay integrating regulatory signals of the cellular environment (1). Stathmin is involved in the regulation of the microtubule filament system. Stathmin binds tubulin in a ternary complex, with 2 tubulins for every stathmin and this complex interferes with microtubule dynamics in vitro and in vivo. Overexpression of several stathmin mutants suggest that stathmin induces depolymerization of interphase and mitotic microtubules in its unphosphorylated state, but is inactivated by phosphorylation in mitosis (2). Stathmin Protein is ideal for investigators involved in Signaling Proteins, Microtubule/Actin Associated Proteins, Cancer, Invasion/Metastasis, and Neurobiology research.


Stathmin Protein is stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. Stathmin Protein is suitable for use in Western Blot. Expect a band approximately ~19kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

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