Anti-DDX58 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

600-401-H15

75931-618EA 635.22 USD

75931-618

Anti-DDX58 Rabbit Polyclonal Antibody

Antibodies

RIG-1 antibody detects the human RIG-1 protein. The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKKε through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus. Anti-RIG-1 antibodies are ideal for investigators involved in infectious disease research.

Anti-RIG-1 Antibody is suitable for use in E,WB, and IHC. Expect a band approximately ~106.6 kDa on specific lysates. Specific conditions for reactivity should be optimized by the end user.

Type: Primary
Antigen: DDX58
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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