RHEB

Supplier: Rockland Immunochemical

009-001-T20S

75931-580EA 388.66 USD

75931-580 75931-582

RHEB

Proteins and Peptides

RHEB control protein-HIS Epitope

Control Protein
PCA Assays
ImmunoBlot

RHEB is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. RHEB is vital in the regulation of growth and cell cycle progression. RHEB has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form. Drosophila RHEB is a direct target of Tsc2 GTPase-activating protein (GAP) activity both in vivo and in vitro. Point mutations in the Drosophila RHEB gene inhibit cell growth while overexpression promotes cell growth. RHEB functions downstream of Tsc1 and Tsc2 in the mTOR signaling pathway. RHEB Protein is ideal for investigators involved in Signaling Proteins, G-Proteins, Angiogenesis, Apoptosis/Autophagy, Cancer, Cardiovascular Disease, ERK/MAPK Pathway, Invasion/Metastasis, and Neurobiology research.

RHEB Protein is stored in 50mM NaPhosphate pH7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.2mM DTT, 25% glycerol. RHEB Protein is suitable for use in Western Blot and Kinase Assay. Expect a band approximately ~21kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

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