PHLPP2

Supplier: Rockland Immunochemical

009-001-S91S

75930-874EA 380.3 USD

75930-874 75930-876

PHLPP2

Proteins and Peptides

PHLPP2 control protein-GST fusion

Control Protein
PCA Assays
ImmunoBlot

PHLPP2 or PH domain and leucine rich repeat protein phosphatase 2 is the important regulators of Akt serine-threonine kinases and conventional/novel protein kinase C (PKC) isoforms. PHLPP1 and PHLPP2 differentially regulated AKT signaling by selectively dephosphorylating the hydrophobic motifs of AKT2 or AKT3. PHLPP may act as a tumor suppressor in several types of cancer due to its ability to block growth factor-induced signaling in cancer cells. PHLPP2 Protein is ideal for investigators involved in Signaling Proteins, Cellular Proteins, AKT/PKB Pathway, Cancer, Phosphatases, and PKA/PKC Pathway research.

PHLPP2 Protein is stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. PHLPP2 Protein is suitable for use in Western Blot and Phosphatase Assay. Expect a band approximately ~56kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

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