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PDE6C

Supplier: Rockland Immunochemical

009-001-S84S

75930-772EA 380.3 USD

75930-772 75930-774

PDE6C

Proteins and Peptides

PDE6C control protein-GST fusion

Control Protein
PCA Assays
ImmunoBlot

PDE6C or phosphodiesterase 6C, cGMP-specific, cone, alpha prime encodes the alpha-prime subunit of cone phosphodiesterase, which is composed of a homodimer of two alpha-prime subunits and 3 smaller proteins of 11, 13, and 15 kDa. PDE6C protein consists of 22 exons spanning approximately 48 kb of genomic DNA. The intron-exon structure of human PDE6C is very similar to that of rod PDE6B (1). A homologous genetic basis of the murine cpfl1 mutant and human achromatopsia linked to mutations in the PDE6C gene and mutations in PDE6C are associated with cone dystrophy type 4 (COD4) (2). PDE6C Protein is ideal to investigators involved in Signaling Proteins, Cellular Proteins, Cardiovascular Disease, and Inflammation research.

PDE6C Protein is stored in 50mM Tris-HCl, pH 7.5, 50mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. PDE6C Protein is suitable for use in Western Blot. Expect a band approximately ~125kDa on specific lysates or tissues. Specific conditions for reactivity should be optimized by the end user.

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