Anti-PXN Mouse Monoclonal Antibody [Clone: PAX-14]

Supplier: Rockland Immunochemical
200-301-P44
75930-740EA 571.49 USD
75930-740
Anti-PXN Mouse Monoclonal Antibody [Clone: PAX-14]
Antibodies
The paxillin gene can be alternatively spliced to include 1 of 2 alternative exons, generating beta and gamma isoforms. Paxillin is a 68-kDa focal adhesion protein that is phosphorylated on tyrosine residues in fibroblasts in response to transformation by v-src, treatment with platelet-derived growth factor, or cross-linking of integrins. The 68-kD protein (paxillin) is a cytoskeletal component that localizes to the focal adhesions at the ends of actin stress fibers in chicken embryo fibroblasts. It is also present in the focal adhesions of Madin-Darby bovine kidney (MDBK) epithelial cells but is absent, like talin, from the cell-cell adherens junctions of these cells. This antibody is suitable for researchers interested in growth factors and signal trasduction.

Anti-Paxillin is useful for Immunohistochemistry and Western Blot. Specific conditions for reactivity should be optimized by the end user. Expect a band approximately ~64.5 kDa corresponding to the appropriate cell lysate or extract.

Type: Primary
Antigen: PXN
Clonality: Monoclonal
Clone: PAX-14
Conjugation:
Epitope:
Host: Mouse
Isotype: IgG1
Reactivity:
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