Anti-P2RX7 Rabbit Polyclonal Antibody

Supplier: Rockland Immunochemical

Anti-P2RX7 Rabbit Polyclonal Antibody

Anti-P2RX7 Rabbit Polyclonal Antibody

600-401-DH9

75930-686EA 635.22 USD

75930-686

Anti-P2RX7 Rabbit Polyclonal Antibody

Antibodies

The purinergic receptor P2X ligand-gated ion channel 7 (P2RX7) belongs to the family of purinoceptors for ATP (1). This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules (1,2). Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression (2). Recent studies have suggested that P2RX7 may play a key role in immune-mediated diseases such as rheumatoid arthritis (3) as well as neuropsychiatric disorders (4).

Anti-P2RX7 Antibody has been tested for use in ELISA and Western Blotting. Specific conditions for reactivity should be optimized by the end user. Expect a band at approximately 68 kDa in Western Blots of specific cell lysates and tissues.

Type: Primary
Antigen: P2RX7
Clonality: Polyclonal
Clone:
Conjugation:
Epitope:
Host: Rabbit
Isotype:
Reactivity:

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